Abstract The spiroindolones, a new class of antimalarial medicines discovered in a cellular screen, are rendered less active by mutations in a parasite P-type ATPase, PfATP4.We show here that S.cerevisiae also acquires Ball - Catcher - Kits mutations in a gene encoding a P-type ATPase (ScPMA1) after exposure to spiroindolones and that these mutatio
Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), influenza, and respiratory syncytial virus (RSV) are highly infectious respiratory viruses that affect people of all ages and are typically associated with mild symptoms and few complications in immunocompetent individuals.However, the risk of severe outcomes (e.g., hospitalizat
Thanks to their excellent photoluminescence quantum yields, their facile and low-cost production, and their processing versatility, CsPbBr3 perovskite nanocrystals (NCs) stand out as excellent candidates to implement light-emitting devices.Elucidating their stimulated emission mechanisms is fundamental to achieve much more efficient and versatile p
Abstract Mapping a sentence into a two-dimensional (2D) representation can flatten nested Coaster Holder semantic structures and build multi-granular span dependencies in named entity recognition.Existing approaches to recognizing named entities often classify each entity span independently, which ignores the spatial structures between neighboring